CLINICAL AND LABORATORY PARAMETERS INFLUENCING VARICOCELECTOMY SUCCESS IN THE TREATMENT OF SUBFERTILE MEN
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Abstract
Varicocele, a condition in which the veins within the scrotum become enlarged, has been studied for over a thousand years. However, there are still many debates surrounding its treatment, particularly with regard to its limited efficacy in improving fertility in men from infertile couples. There are various clinical and laboratory factors that may impact the success of varicocele repair. Recent analysis suggests that evidence on the predictors of varicocele repair efficacy remains controversial. However, initial semen parameters such as sperm concentration and/or TMSC may be relatively important in predicting the success of varicocelectomy in treating male infertility.
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References
Abbosov, S., Akilov, F., Mukhtarov, S. T., Shomarufov, A. B., & Mirkhamidov, D. K. (2024). A novel approach to treatment and prophylaxis of recurrent bladder neck contracture. European Urology Open Science, 59(Supplement 1), S63.
Abbosov, S., Shomarufov, A. B., Akilov, F., & Mukhtarov, S. T. (2023). Balloon dilation role in the treatment and prophylaxis of bladder neck contracture. European Urology Open Science, 57(Suppl 2), S432.
Abdel-Meguid, T. A., Al-Sayyad, A., Tayib, A., & Farsi, H. M. (2011). Does varicocele repair improve male infertility? An evidence-based perspective from a randomized, controlled trial. European Urology, 59(3), 455–461.
Abdelbaki, S. A., Sabry, J. H., Al-Adl, A. M., & Sabry, H. H. (2017). The impact of coexisting sperm DNA fragmentation and seminal oxidative stress on the outcome of varicocelectomy
in infertile patients: A prospective controlled study. Arab Journal of Urology, 15(2), 131–139.
Akilov, F. A., Mukhtarov, S. T., Shomarufov, A. B., Abbosov, S. A., Shavakhabov, S. S., Mirkhamidov, D. K., Giyasov, S. I., Kasimov, S. S., & Abdukarimov, O. O. (2023). Assessment of semen parameters after microsurgical varicocelectomy in men from infertile couples. Vestnik Urologii/Urology Herald, 11(3), 16–22.
Al-Adl, A. M., El-Karamany, T., Issa, H., & Zaazaa, M. (2014). The influence of antisperm antibodies, intratesticular haemodynamics and the surgical approach to varicocelectomy on seminal variables. Arab Journal of Urology, 12(4), 309–317.
Almekaty, K., Zahran, M. H., Zoeir, A., Minhas, S., & Salem, K. (2019). The role of artery-preserving varicocelectomy in subfertile men with severe oligozoospermia: a randomized controlled study. Andrology, 7(2), 193–198.
Asafu-Adjei, D., Judge, C., Deibert, C. M., Li, G., Stember, D., & Stahl, P. J. (2020). Systematic Review of the Impact of Varicocele Grade on Response to Surgical Management. The Journal of Urology, 203(1), 48–56.
Ates, E., Ucar, M., Keskin, M. Z., & Gokce, A. (2019). Preoperative neutrophil-to-lymphocyte ratio as a new prognostic predictor after microsurgical subinguinal varicocelectomy. Andrologia, 51(2).
AUA|ASRM. (2020). Diagnosis and Treatment of Infertility in Men: AUA/ ASRM Guideline. American Society of Reproductive Medicine, October, 1–53.
B Shomarufov, A. (2023). Varicocelectomy in Male Subfertility Treatment: ‘“Updated”’ Indications for Surgery. Journal of Nephrology & Endocrinology Research, 1–2.
Baker, K., McGill, J., Sharma, R., Agarwal, A., & Sabanegh, E. (2013). Pregnancy after varicocelectomy: Impact of postoperative motility and DFI. Urology, 81(4), 760–766.
Bozhedomov, V. A., Lipatova, N. A., Alexeev, R. A., Alexandrova, L. M., Nikolaeva, M. A., & Sukhikh, G. T. (2014). The role of the antisperm antibodies in male infertility assessment after microsurgical varicocelectomy. Andrology, 2(6), 847–855.
Bozhedomov, V. A., Shomarufov, A. B., Bozhedomova, G. E., D, O. A., Kamalov, D. M., & Kamalov, A. A. (2021). Varicocele and reproductive function: epidemiology and infertility risk (the eamination of 3632 patients). Urologiia (Moscow, Russia : 1999), 3, 122–128.
Bryniarski, P., Taborowski, P., Rajwa, P., Kaletka, Z., Życzkowski, M., & Paradysz, A. (2017). The comparison of laparoscopic and microsurgical varicocoelectomy in infertile men with varicocoele on paternity rate 12 months after surgery: a prospective randomized controlled trial. Andrology, 5(3), 445–450.
Cantoro, U., Catanzariti, F., Lacetera, V., Quaresima, L., Giovanni, M., & Polito, M. (2015). Percentage change of FSH value: New variable to predict the seminal outcome after varicocelectomy. Andrologia, 47(4), 412–416.
Chen, S. S. (2014). Predictive factors of successful redo varicocelectomy in infertile patients with recurrent varicocele. Andrologia, 46(7), 738–743.