CHARACTERISTICS OF HEART FUNCTIONAL DISORDERS IN GOUT DISEASE
Main Article Content
Abstract
In our study, 88 patients (all male) were selected to examine the structural and functional status of the myocardium in patients with gout. EchoCG screening was performed in patients with gout (recurrent and chronic).ECG and EchoCG examinations revealed changes in the cardiovascular system in 82% of patients. Moreover, while LV hypertrophy was detected in 43% of patients, the presence of AH was noted in 62% of these patients. At the same time, an average of 70% of patients with EchoCG were diagnosed with the following types of valvular lesions: IVB thickening - 50% of cases, LV posterior wall thickening - 44%, LA hypertrophy - 36%, LVDD - 31.5%. Various disturbances in heart rhythm and conduction have also been reported, with a predominance of ventricular extra systoles. At the same time, the above changes have been found to be more common in chronic forms of the disease. By the way, in this study it was found that the development of cardiopathy is directly related to the concentration of uric acid, xanthine oxidase in the blood.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
Nasonov E.L. 2015; Nasonov E.L., Karateev D.E., Satybaldyev A.M. and others., 2015;
Adams P.F. Current estimates from the National Health Interview Survey, 1996 / P.F. Adams, G.E. Hendershot, M.A. Marano // Vital Health Stat. - 1999.-Vol. 10.-p. 2000;
Saag K.G. Recent advances in the epidemiology of gout / K.G. Saag, T.R. Mikuls // Curr. Rheumatol. Rep. - 2005. - Vol. 7. - pp. 235-241;
Terkeltaub R.A. Clinical practice. Gout / R.A. Terkeltaub // N. Engl. J. Med. - 2003. - Vol. 349. - pp. 1647-1655.
Wallace K.L. Increasing prevalence of gout and hyperuricemia over 10 years among older adults in a managed care population / K.L. Wallace, A.A. Riedel, N. Joseph-Ridge // J. Rheumatol. -2004. -Vol. 31. -pp. 1582-1587.
Eliseev M.S. Clinical signs of metabolic syndrome in gout / M.S. Eliseev, V.G. Barskova, V.A. Nasonova // Clinical gerontology. - 2006. - Т. 12, № 2. - pp. 29-33
Toirov E.S., Toirov D.R., Solovev S.K. / Gout diagnosis and treatment - Tashkent-Uzbekistan-2020.
Toirov, Doston Rustamovich, and Doniyor Khasanovich Berdiyev. "CHARACTERISTICS OF CARDIOHEMODYNAMIC DISORDERS IN GOUT DISEASE." Scientific progress 2.3 (2021): 775-784. https://cyberleninka.ru/article/n/podagra-kasalligida-kardiogemodinamik-buzilishlar-o-ziga-xosligi.
Rustamovich T. D., Hasanovich B. D. COMORBID FACTORY OF HEART BLOOD VEHICLES AND METABOLIC SYNDROME IN PATIENTS // Archive of Conferences. - 2021. - Т. 14. - №. 1. - p. 18-24.https: //www.conferencepublication.com/index.php/aoc/article/download/722/772
Toirov D. R., Maxmudova X. D. CARDIOVASCULAR DAMAGE IN PATIENTS WITH GOUT DISEASE // Scientific progress. - 2021. - Т. 2. - №. 2. - p. 242-249.https: //cyberleninka.ru/article/n/podagra-kasalligi-bilan-o-rigan-bemorlarda-yurak-on-tomir-zararlanishlari.
Yarmukhamedova, S., Nazarov, F., Mahmudova, X., Vafoeva, N., Bekmuradova, M., Gaffarov, X., ... & Xusainova, M. (2020). Features of diastolic dysfunction of the right ventricle in patients with hypertonic disease. Journal of Advanced Medical and Dental Sciences Research, 8(9),. -p.74-77. http: //jamdsr.com/uploadfiles/17vol8issue9p74-77.20200905031856.pdf
Toirov D. R., Toirov E. S. Metabolic syndrome in gout: relationship with functional disorders of the kidneys // Questions of science and education. – 2019. – no. 28 (77). – p. 46-51.https://cyberleninka.ru/article/n/metabolicheskiy-sindrom-pri-podagre-vzaimosvyaz-s-funktsionalnymi-narusheniyami-pochek
Bekmuradova M. S., Gafforov Kh. Kh., Yarmatov S. T. Significance of the determination of brain natriuretic peptide in the process of diagnosing chronic heart failure // Achievements of science and education. – 2020. – no. 4 (58). https://cyberleninka.ru/article/n/znachenie-opredeleniya-mozgovogo-natriyureticheskogo-peptida-v-protsesse-diagnostiki-hronicheskoy-serdechnoy-nedostatochnosti
Bekmuradova M. S., Makhmudova Kh. D., Nazarov F. Yu. Diagnostic significance of brain natriuretic peptide in the detection of chronic heart failure //Scientific progress. - 2021. - Vol. 2. - No. 1. - pp. 810-814.
Yarmukhamedova S. Kh., Bekmuradova M. S., Nazarov F. Yu. Diagnostic value of natriuretic peptide in identifying patients with asymptomatic systolic or diastolic dysfunction // Achievements of science and education. – 2020. – no. 8 (62). – pp. 84-88.https://cyberleninka.ru/article/n/diagnosticheskaya-tsennost-natriyureticheskogo-peptida-pri-vyyavlenii-patsientov-s-bessimptomnoy-sistolicheskoy-ili-diastolicheskoy