CHANGES IN THE HUMAN LUNG DURING THE EMBRYONIC PERIOD

Authors

  • Ashuraliyeva Gulhumor Kahhorovna Assistant of the Department of Anatomy and Clinical Anatomy Andijan State Medical Institute, Uzbekistan

Abstract

During  embryonic  histogenesis  of  human  lungs,  early  morpho - functional  differentiation  of apudocytes is observed. In the lungs of young children with an inflammatory pathology of this organ, endocrine structures are detected with great constancy, and  their number  is  large. The  longer  the disease lasts, the more apudocytes and NETs are found  in the bronchi and respiratory tract. In large bronchi there are more endocrine structures than  in small ones. Inflammatory lung diseases  in early postnatal ontogenesis are a predisposing factor for apudocyte hyperplasia.

References

Young LR, Brody AS, Inge TH, Acton JD, Bokulic RE, Langston C, Deutsch GH.Neuroendocrine cell distribution and frequency distinguish neuroendocrine cell hyperplasia of infancy from other pulmonary disorders. Chest. 2011 May; 139 (5): 1060-71.

Koo CW, Baliff JP, Torigian DA, Litzky LA, Gefter WB, Akers SR Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. Am J Roentgenol. 2010 Sep; 195 (3): 661-8.

Linnoila RI. Functional facets of the pulmonary neuroendocrine system Laboratory Investigation (2006) 86, 425–4440

Rizvi SM, Goodwill J, Lim E, Yap YK, Wells AU, Hansell DM, Davis P, Selim AG, Goldstraw P, Nicholson AG. The frequency of neuroendocrine cell hyperplasia in patients with pulmonary neuroendocrine tumors and non- neuroendocrine cell carcinomas. Histopathology.2009 Sep; 55(3): 332-7.

DaviesSJ, Gosney R, HansellDM , WellsAU, du BoisRM, BurkeMM, MN Sheppard, and NicholsonAG. Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: an under–recognized spectrum of disease. Thorax. Mar 2007; 62 (3): 248-252.

Kazakbayeva D. The words with the semantics of "ear" pragmatic properties in the Uzbek language, InterConf 2021, p224-229

D. Kazakbayeva, S. Qodirov. Ingliz va o'zbek tillarida "quloq" semantik maydoni konstituentlari tipologiyasi, Science and education 2 (4), 2021, p441-452.

Published

2022-02-20

Issue

Section

Articles