INDOOR AIR QUALITY MONITORING AMONG A POPULATION WITH KNOWN RESPIRATORY HEALTH STATUS: A CASE STUDY OF NAVOIY CITY
DOI:
https://doi.org/10.17605/Keywords:
Indoor air quality (IAQ), pediatric asthma, respiratory health, PM₂.₅, respirable suspended particulates (RSP), nitrogen dioxide (NO₂), formaldehyde (HCHO), volatile organic compounds (VOCs), indoor pollutants, bioaerosols, endotoxins, dust mite allergens, Der p1, environmental monitoring, passive diffusion sampling, gravimetric analysis, ELISA, case-control study, double-blind study, indoor exposure assessment, residential environment, industrial pollution, children's health, epidemiological risk assessment, microclimate.Abstract
Indoor air quality (IAQ) is a critical public health determinant, yet its relationship with pediatric respiratory morbidity in heavy-industrial, arid regions remains understudied. This paper introduces the methodological framework and preliminary validation results of the Navoiy Community Asthma Project (NaHAL), which evaluates the impacts of indoor chemical and biological pollutants on children with known asthma status in Navoiy City, Uzbekistan. A 2.5-year matched case-control study (n = 500 children; 250 asthmatics, 250 healthy controls) was established across residential sectors of Navoiy. Environmental monitoring was deployed for 5 continuous days in living rooms and bedrooms using a double-blind approach. Gaseous pollutants (NO2, HCHO, VOCs) were captured via passive diffusion tubes, while respirable suspended particulates (PM2.5) were measured via active gravimetric sampling. Dust samples were vacuum-extracted from carpets and mattresses to analyze endotoxins and dust mite allergens (Der p1).
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