THE USE OF NANOTECHNOLOGIES IN HISTOLOGICAL RESEARCH
Keywords:
Nanotechnology, histology, nanoparticles, immunogold, fluorescent labeling, hyperspectral microscopy, upconversion, Kupffer cells, astrocytes, biodistribution.Abstract
This article explores the application of nanotechnologies in histological research. It highlights the role of classical and advanced histological methods in evaluating the distribution, detection, and biological impact of nanoparticles in tissues. Studies demonstrate how ultrasmall iron oxide and gold nanoparticles distribute in the liver, brain, and other organs. Techniques such as enhanced darkfield microscopy, hyperspectral imaging, and upconversion fluorescence offer novel visualization strategies. These nanotechnologies enable greater resolution, speed, and multiplex molecular detection. The article discusses the diagnostic and research potential of these approaches in the future of biomedical science.
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