THE ROLE OF ALPHA-ADRENOMIMETICS IN THE MANAGEMENT OF OBSTRUCTIVE SYNDROMES IN EMERGENCY SITUATIONS

Authors

  • Dusmatov Umidbek Alisher ugli

Abstract

Obstructive syndromes in emergency settings, such as upper airway obstruction, anaphylaxis, or severe exacerbations of asthma, pose a significant threat to patient survival. The use of alpha-adrenomimetics (α-adrenergic agonists) has been a cornerstone in their management due to their ability to reduce mucosal edema, enhance airway patency, and stabilize hemodynamic parameters. This review examines the pharmacodynamics and pharmacokinetics of α-adrenergic agonists, their clinical applications, administration protocols, and associated risks in emergency scenarios.

References

Smith, J., et al. “Efficacy of Racemic Epinephrine in Pediatric Croup: A Randomized Controlled Trial.” Journal of Emergency Medicine, 2023.

Brown, S. “Management of Anaphylaxis in the Emergency Department.” Annals of Emergency Medicine, 2022.

Wilson, D., and Lee, K. “Alpha-Adrenergic Agonists in Shock: Clinical Applications and Outcomes.” Critical Care Medicine, 2021.

National Institute for Clinical Excellence (NICE). “Guidelines on Airway Management in Emergency Settings.” 2022.

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Published

2024-12-16

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Section

Articles