ANTIPHOSPHOLIPID SYNDROME AS A CAUSE OF ISCHEMIC STROKE IN YOUNG AGE

Abstract

Hypercoagulation syndrome is an actual multidisciplinary problem of the last decade. Hemostasis disorders leading to hypercoagulation syndrome are manifested by various diseases in neurology, obstetrics, rheumatology, surgery. Antiphospholipid syndrome is the most common form of hypercoagulation syndrome and most often develops at a young age, in children and even newborns, and in females 5 times more often than in males. The causes and mechanism of antiphospholipid syndrome are not completely clear. The defeat of the central nervous system in this syndrome can have both ischemic (violation of cerebral circulation) and non-ischemic (primary immune-mediated damage to the nervous system) genesis. The spectrum of neurological disorders associated with antiphospholipid syndrome is very wide: from cerebral circulatory disorders, migraines and migraine headaches to chorea and epileptic seizures. Thus, antiphospholipid syndrome requires special attention for timely and early diagnosis for the prevention of severe complications.